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John D Spencer Selected Research

Ribonuclease 7

11/2021Ribonuclease 7 polymorphism rs1263872 reduces antimicrobial activity and associates with pediatric urinary tract infections.
1/2015Ribonucleases 6 and 7 have antimicrobial function in the human and murine urinary tract.
5/2014An endogenous ribonuclease inhibitor regulates the antimicrobial activity of ribonuclease 7 in the human urinary tract.
7/2011Ribonuclease 7 is a potent antimicrobial peptide within the human urinary tract.

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John D Spencer Research Topics

Disease

5Infections
12/2021 - 07/2011
3Urinary Tract Infections (Urinary Tract Infection)
11/2021 - 10/2016
3Infertility (Sterility)
01/2015 - 07/2011
2Pyelonephritis
11/2019 - 05/2014
1Pyuria
01/2022
1Acute Kidney Injury (Acute Renal Failure)
12/2021
1Birth Weight (Birth Weights)
12/2021
1Hemolysis
12/2021
1Bacteriuria
11/2019
1Cystitis
11/2019
1Sepsis (Septicemia)
11/2019
1Cicatrix (Scar)
10/2016
1Vesico-Ureteral Reflux (Vesicoureteral Reflux)
10/2016

Drug/Important Bio-Agent (IBA)

5Antimicrobial PeptidesIBA
11/2021 - 07/2011
4Ribonuclease 7IBA
11/2021 - 07/2011
2Anti-Bacterial Agents (Antibiotics)IBA
12/2021 - 10/2016
1Biomarkers (Surrogate Marker)IBA
01/2022
1CreatinineIBA
01/2022
1leukocyte esteraseIBA
01/2022
1DiureticsIBA
12/2021
1Polyurethanes (Polyurethane)IBA
12/2021
1Adenosine Monophosphate (AMP)IBA
11/2019
1DefensinsIBA
10/2016
1DNA (Deoxyribonucleic Acid)IBA
10/2016
1Ribonucleases (Ribonuclease)IBA
01/2015
1Pancreatic Ribonuclease (Ribonuclease A)IBA
01/2015
1Messenger RNA (mRNA)IBA
01/2015
1Proteins (Proteins, Gene)FDA Link
01/2015
1Peptides (Polypeptides)IBA
05/2014

Therapy/Procedure

1Therapeutics
12/2021
1Antibiotic Prophylaxis
10/2016